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Three BFFs took a drawing class together and now want to practice. The girls get together and wait for their model to arrive. When a guy shows up, they are surprised because they expected a girl. However, they think they can make it work and have the guy stay. He removes his clothes and reveals a boner! The girls are taken aback at the sight of his big dick. After the initial shock, they start drawing. Now I want to ask you, would you like to pose nude, proudly with an erection in front of three teen girls? One of the girls goes in for a closer look and starts to touch the erect cook. To draw his body as best she can, the girl moves his cock from side to side, lifts his hanging balls and her hand makes his cock throb even harder. She thinks she can help him with his erection if she places it in her mouth and makes him cum. The guy says ok, go ahead and he keeps posing in front of her friends having his cock sucked. The other girls keep drawing but his cock looks so tasty! Their friend is making slurping sounds sucking furiously on his erect dick. Her eyes closed in pleasure, her hand caressing his scrotum. She encourages the other girls to give it a try. Soon enough, all three are on their knees in front of their nude model. All three girls take turns sucking the enormous dick and the balls. They drop their pencils so they can fully focus on sucking his cock!NAKED GIRLS IN A THREESOME, FOURSOME AND MORE-SOME SEX:What could be better than three teens sucking on your cock together, looking at you and purring with pleasure? When all of them get aroused, the girls start taking their clothes off. The busty ones insisted on some titty fucking first. The other wants to have her booty penetrated from behind, so she gets her bare ass against the model and gets fucked doggy-style while the other girls fondle the balls. Seeing how the first girl screams with pleasure, the other two want a piece of that action. Three naked girls got into a pyramid position. Three pussies in a raw, for you pleasure! The sight that any man would like to see at least once in his life! Stick your cock in any cunt you want! He is going back and forth from one pussy to the next, from one wet slit to the next, up and down. The naked girls remain in the same position and he licks their young cunts, moving his tongue along their entire length of their ass cracks! They even get into a sex train with each girl eating some delicious pussy. Then all three naked girls roll over on their backs and spread their legs. His gaze goes from one pussy to the other and back again. He is trying to decide which pussy to fuck first. The feeling is incredible, moving so swiftly from one pussy to another! All of them are dripping wet and ready to squirt all over their drawing equipment. To make an even bigger mess, the model wants to cum all over the naked girls. They get in front of him and get their pretty faces covered in his cum. No wonder they want to work together again.
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Avlimil, a dietary supplement advertised to ameliorate female sexual dysfunction, is a mixture of eleven herbal components, and some herbal constituents of Avlimil (including black cohosh, licorice, red raspberry, red clover and kudzu) contain phenolic compounds, which are suggested to have estrogenic, anti-estrogenic, or androgenic potential for relieving menopausal symptoms. We hypothesize that Avlimil could modulate the growth of estrogen receptor positive human breast cancer (MCF-7) cells in vitro and in vivo. A dimethylsulfoxide (DMSO) extract of Avlimil (0.001-100 microg Avlimil powder equivalents/mL media) was tested for its estrogenic and anti-estrogenic effects on the growth of MCF-7 cells in vitro. We observed that the DMSO extract of Avlimil at low concentrations (0.1-50 microg/mL media) dose-dependently increased MCF-7 cell proliferation in vitro, and Avlimil DMSO extract at 100 microg/mL inhibited the growth of MCF-7 cells in vitro. Avlimil and some constituents (black cohosh and licorice roots) of Avlimil were fractionated by using sequential solvent extraction (hexane, ethyl acetate, and methanol) and the activities of the fractions were monitored by effects on the growth of MCF-7 cells. Depending on dosage (0.1-100 microg/mL media) both stimulatory and inhibitory effects of the extracts on the growth of MCF-7 cells were observed. The effect of dietary Avlimil at dosages approximating human intake was evaluated using ovariectomized mice implanted with MCF-7 cells. Animals were fed diets containing 500 ppm or 1000 ppm Avlimil for 16 weeks. Dietary Avlimil at 500 ppm stimulated MCF-7 tumors, but Avlimil at 1000 ppm had no apparent effect on the growth of MCF-7 tumors. The observation of stimulated tumor growth in the absence of uterine wet weight gains suggest that estrogenic/anti-estrogenic effects of Avlimil we observed may be dosage- and target tissue-specific and that Avlimil may not be safe for women with estrogen-dependent breast cancer. The different biological effects of fractionated Avlimil components and the different concentration dependencies warrant further compound identification and dose-response studies, especially at recommended intake levels that could have estrogenic effects in women.
Weighted frequencies were calculated to assess the prevalence of women who have used Angling, Rocking, Shallowing, Pairing, and their sub-forms to make vaginal stimulation and penetration more pleasurable. We excluded from analysis of each item any participant whose response to that item was missing. IBM SPSS Statistics software was used for all analyses.
As shown in Table 3, 76.4% of women had ever used any form of Rocking (i.e. the base of a penis or sex toy rubbing against the clitoris constantly during penetration, by staying all the way inside the vagina rather than thrusting in and out) to enhance their pleasure during vaginal penetration. Nearly three-quarters of women (70.2%) had ever engaged in Rocking with a penis to make penetration more pleasurable for themselves. In contrast, one-third of women had ever used Rocking with a sex toy (35.8%), to make penetration more pleasurable.
As shown in Table 4, approximately 4 out of 5 women (83.8%) had ever used any form of Shallowing (e.g. being touched just at the entrance to the vagina) to enhance their pleasure during penetration. A majority of women had ever done Shallowing with a penis tip (67.1%) or with a tongue or lips (69.7%) to make penetration more pleasurable. A slightly smaller proportion of women had used Shallowing with a fingertip (60.4%) to enhance their pleasure from penetration. Shallowing was less commonly done with a sex toy (37.8%).
Table 5 illustrates the ways in which women reported that using a Shallowing technique enhanced their sexual pleasure during penetration that followed Shallowing. About 40% of women noted more pleasure, while a quarter reported stronger orgasms. Only 10.1% thought that their likelihood of orgasm was increased. One-third of women (37.4%) suggested that their pleasure was impacted, but in a way that did not follow a specific pattern.
As shown in Table 6, 69.7% of women have ever used a Solo Pairing or Partner Pairing technique (e.g. woman stimulating her clitoris with a finger or a partner doing so while the partner simultaneously penetrates her vagina) to make penetration more pleasurable. Forty percent of women had used Solo Pairing to make penetration more pleasurable; about one-third of women had ever done so with a finger, and 20% had ever done so with a sex toy. About half of women had engaged in Partner Pairing to make penetration more pleasurable (49%); Partner Pairing was more commonly done with a finger (43.1%) than with a sex toy (17.5%).
Data from this U.S. nationally representative survey provide descriptions of and prevalence estimates for four techniques women have discovered to make vaginal penetration more pleasurable: Angling, Rocking, Shallowing, and Pairing. Our findings contribute to the growth of a person-centered approach to sexual pleasure, previously underexplored in published literature, through detailed documentation of specific, newly identified forms of vaginal stimulation and penetration, as well as evaluation of technique prevalence. Knowledge of these techniques can enable women to better identify their own preferences, communicate about them and advocate for their sexual pleasure.
Some genes on the X chromosome escape X-inactivation. Many of these genes are located at the ends of each arm of the X chromosome in areas known as the pseudoautosomal regions. Although many genes are unique to the X chromosome, genes in the pseudoautosomal regions are present on both sex chromosomes. As a result, men and women each have two functional copies of these genes. Many genes in the pseudoautosomal regions are essential for normal development.
46,XX testicular difference of sex development is a condition in which individuals with two X chromosomes in each cell, the pattern typically found in females, have a male appearance. In most individuals with 46,XX testicular difference of sex development, the condition results from an abnormal exchange of genetic material between chromosomes (translocation). This exchange occurs as a random event during the formation of sperm cells in the affected person's father. The translocation affects the gene responsible for development of a fetus into a male (the SRY gene). The SRY gene, which is normally found on the Y chromosome, is misplaced in this condition, almost always onto an X chromosome. A fetus with an X chromosome that carries the SRY gene will develop as a male despite not having a Y chromosome. 2ff7e9595c
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